CREON (Pancrelipase Delayed-Release Capsules) for the treatment of exocrine pancreatic insufficiency
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چکیده
منابع مشابه
Delayed release pancrelipase for the treatment of pancreatic exocrine insufficiency associated with cystic fibrosis
Pancreatic enzyme replacement therapy (PERT) is the only treatment for malabsorption in cystic fibrosis (CF) caused by pancreatic insufficiency (PI). PI occurs in approximately 85% of patients with CF. PERT overcomes some, but not all the signs and symptoms of malabsorption. Clinical parameters such as growth, abdominal pain, diarrhea and gassiness, commonly used to adjust PERT dosing, are show...
متن کاملDelayed release pancrelipase for treatment of pancreatic exocrine insufficiency associated with chronic pancreatitis
Pancreatic enzyme supplements (PES) are used in chronic pancreatitis (CP) for correction of pancreatic exocrine insufficiency (PEI) as well as pain and malnutrition. The use of porcine pancreatic enzymes for the correction of exocrine insufficiency is governed by the pathophysiology of the disease as well as pharmacologic properties of PES. Variability in bioequivalence of PES has been noted on...
متن کاملPancrelipase: an evidence-based review of its use for treating pancreatic exocrine insufficiency
Pancreatic exocrine insufficiency (PEI) is often observed in patients with pancreatic diseases, including chronic pancreatitis, cystic fibrosis, and tumors, or after surgical resection. PEI often results in malnutrition, weight loss and steatorrhea, which together increase the risk of morbidity and mortality. Therefore, nutritional interventions, such as low-fat diets and pancreatic enzyme repl...
متن کاملPancreatic exocrine insufficiency: diagnosis and treatment.
Pancreatic insufficiency is a major consequence of pancreatic diseases leading to a loss of pancreatic parenchyma, obstruction of the main pancreatic duct, decreased pancreatic stimulation, or acid-mediated inactivation of pancreatic enzymes. In addition, gastrointestinal and pancreatic surgical resections are frequent causes. Clinical manifestations include abdominal cramps, steatorrhea and ma...
متن کاملExocrine Pancreatic Insufficiency
Exocrine pancreatic insuffiency is loss of ability to properly digest food due to inadequate pancreatic enzyme activity. The etiology of exocrine pancreatic insuffiency, in humans, is mostly chronic pancreatitis or diseases affecting pancreas such as cytsic fibrosis, Shwachman-Diamond syndrome. It may also occur as a complication of gastric or pancreatic surgical procedures due to decrease of e...
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ژورنال
عنوان ژورنال: Advances in Therapy
سال: 2010
ISSN: 0741-238X,1865-8652
DOI: 10.1007/s12325-010-0085-7